Esters of quinoxaline-7-carboxylate-1,4-di-N-oxide as Trichomonas vaginalis triosephosphate isomerase inhibitors
Trichomoniasis is a public health problem worldwide.Trichomoniasis treatment consists of the use of nitroimidazole derivatives; however, therapeutic ineffectiveness occurs in 5 to 20 % of the cases.Therefore, it is essential to propose new pharmacological agents against this disease.In this work, esters of quinoxaline-7-carboxylate-1,4-di-N-oxide (